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Biopsy of small intestine with coeliac disease
Biopsy of small intestine with coeliac disease

Coeliac disease is a chronic, autoimmune disease mainly affecting the small intestine, caused by an abnormal immune system response to gluten. The disease's classic form can affect any age group, causing symptoms of malabsorption. Non-classic coeliac disease is more common in adults, characterised by vague abdominal symptoms and complications in organs outside the gastrointestinal tract. To those with a genetic predisposition to the condition, eating gluten causes inflammation in the small intestine, damaging its lining and leading to malabsorption. Diagnosis is based on symptoms, blood tests, and biopsies of the small intestine. It is treated by implementing a gluten-free diet; symptoms can improve within days. Diagnoses have increased due to increased awareness and availability of blood testing, but it is still thought to be underdiagnosed. Most people develop the disease before the age of ten; it is slightly more common in women than in men. (Full article...)

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Cruz de Clavos
Cruz de Clavos
  • ... that the original Cruz de Clavos (replica pictured), which included 260 nails representing women killed in Chihuahua, was later stolen despite being anchored to the ground?
  • ... that People in Trouble was based on Sarah Schulman's experiences of the AIDS crisis, Donald Trump, and having an affair with a married woman?
  • ... that medieval sources disagree on exactly how Count Henry II of Champagne died in a fall, variously blaming a broken window bar, a carpet, or even a falling dwarf?
  • ... that one archaeologist suggested that the shape of the Baptistery of Bekalta facilitated multiple baptisms at the same time?
  • ... that Jessie Catherine Couvreur became so famous for her public lectures about Australia that she was invited to a private meeting with King Leopold II of Belgium?
  • ... that the first Sokoban video game featured text-based graphics and only five levels, until a salesman saw it and suggested that it had commercial potential?
  • ... that Sophie Tea once paid for accommodation by painting a cow?
  • ... that Docip provided a computer room for indigenous peoples' representatives in international negotiations?
  • ... that Indonesian diplomat Triyono Wibowo attempted to bring Komodo dragons and orangutans to Slovenia?

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April 15: Universal Day of Culture; Day of the Sun in North Korea; Jackie Robinson Day and Tax Day in the United States

Henry VI, Holy Roman Emperor
Henry VI, Holy Roman Emperor
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Curtis Granderson
Curtis Granderson

In Major League Baseball (MLB), the 20–20–20 club is the group of batters who have collected 20 doubles, 20 triples, and 20 home runs in a single season. Frank Schulte was the first to achieve this, doing so in 1911. The last players to reach the milestone – Curtis Granderson (pictured) and Jimmy Rollins – attained 20–20–20 during the 2007 season. This marked the first time that two players accomplished the achievement in the same season. In total, seven players are members of the 20–20–20 club. Of these, five were left-handed batters, one was right-handed, and one was a switch hitter, meaning he could bat from either side of the plate. Two players – George Brett and Willie Mays – are members of the 3,000-hit club, and Mays is a member of the 500 home run club. (Full list...)

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Baspa Valley

The Baspa Valley is the river valley of the Baspa River, which is fed by Himalayan glaciers and flows through the district of Kinnaur, in the northern Indian state of Himachal Pradesh, until it meets the Sutlej. This photograph shows a panoramic view of the Baspa Valley covered in snow in March 2025. The town of Sangla is on the right-hand side of the image.

Photograph credit: UnpetitproleX

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